Research Treatment Study for 12-21 Year Olds with ASD
Do you have a child between the ages of 12 and 21 who has an autism spectrum disorder?
The STX209 (Arbaclofen) Seaside Therapeutics Research Study at The Children's Hospital of Philadelphia is looking for participants.
What are the goals of this research study?
We are doing a research study to learn more about an investigational drug called Arbaclofen. We want to know if this drug helps to treat symptoms of autism spectrum disorders, including social withdrawal, listlessness, or inactivity.
Who can be a part of this research study?
We are looking for individuals ages 12 to 21 who have been diagnosed with an autism spectrum disorder and who exhibit certain behaviors such as listlessness and inactivity, isolation from other children and adults, or fixed facial expressions and lack of emotional responses.
What will participants be asked to do?
We will ask you and your child to come to The Children's Hospital of Philadelphia a total of 7 times over the course of about 5 months for study visits. The study involves administration of either the study drug or placebo by mouth for 12 weeks followed by 28 days of withdrawal. Most visits will last between one and two hours, although visits toward the beginning and end will last longer. During each of the visits, a doctor will talk with you about how your child is doing. We'll check your child's weight, height, pulse, blood pressure, and heart function. We'll also take blood samples at certain visits. An electrocardiogram (ECG) will be performed to monitor your heart beating and will be performed twice during the study. As the parent, you will need to answer some written questions about your child and record each dose of study medication taken by your child. For each visit to our center, a small payment may be offered to offset travel expenses.
What are the benefits of taking part in this research study?
If you take part in this study, there may or may not be direct medical benefit to your child. However, your child will receive study-related care, monitoring, and frequent visits with the study doctor at no cost to you. We'll give you information about autism spectrum disorders and possible treatment options.
I want to help! Who do I call?
If you are interested in learning more about participation, please respond by phone or email with your phone number and the best time to reach you, and one of the members of our team will call you.
autismMatch is a tool that quickly and easily connects individuals and families in the Mid-Atlantic and adjacent regions with autism research studies on treatment, diagnosis, genetics, and brain imaging, as well as studies focused on common co-occurring problems related to sleep and anxiety. Children and adults with or without autism are welcome to join autismMatch. Click here to enroll online